This site offers information on prohibited antimicrobial substances detected in seafood products during inspections conducted by the US Food and Drug Administration (FDA).   Toxicity, increased antimicrobial resistance and cancer are primary FDA health and safety concerns for prohibiting the use of the following antimicrobial agents in food:

  • Chloramphenicol
  • Crystal Violet (Gentian Violet), Brilliant Green, Malachite Green and Leucomalachite Green
  • Fluoroquinolones
  • Nitrofurans

Links on this site lead to: background information on the health and safety issues, generic HACCP plans serving as guidelines for preventing the hazard in products, FDA analytical methods, and commercially developed rapid detection kits to assist in screening for the prohibited agents.


This site is sponsored by a grant from the US Department of Agriculture in cooperation with California Sea Grant and UC Agriculture and Natural Resources.


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